Optimized IFS

Interferential stimulation (IFS), once optimized for modulation depth, can achieve more focal modulation of stimulation intensity than conventional stimulation with a single frequency, both at the cortical surface and deep in the brain. If one does not care about if the stimulation reaches non-target area, then optimized IFS gives the exactly same solution as the optimized conventional transcranial electrical stimulation.

For more details, see Yu Huang, Abhishek Datta, Lucas C Parra, Optimization of interferential stimulation of the human brain with electrode arrays, bioRxiv 783423, May 13, 2020.

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